Jedoch war ein dezenter Alters- und Gendereffekt zuīeobachten. Zwischen diesen beiden Gruppen zeigte keinen signifikanten Unterschied POWG und 132,02 µg/l für die Kontrollgruppe. Serumselenkonzentration (Ls-mean) betrug 134,86 µg/l für Patienten mit Kovarianz-, Perzentilenregressions-, Alters- und Genderanalyse. Selenkonzentration wurde von 39 Serumproben (22 pOWG, 17 Kontrollen)Īnhand der Inductively coupled Plasma-sector Field Mass Spectrometry Verhältnis zu der bislang einzig beschriebenen Kohorte in den US Wurden auf mögliche Alters- und Gendereffekte hin untersucht sowie ins Diese Ergebnisse der vorliegenden deutschen Kohorte
Primärem Offenwinkelglaukom (pOWG) im Vergleich zu einer Kontrollgruppe Das Zielĭer vorliegenden Studie war es, den Serumselenspiegel bei Patienten mit Unterliegt damit kulturellen und ethnischen Variabilitäten. Selengehalt im Serum wird unter anderem über die Ernährung gesteuert und Spurenelement Selen (Se) wird eine Mitbeteiligung postuliert.
Können über oxidativen Stress vermittelte molekulare Interaktionen inĭie Pathogenese der Glaukomerkrankung eingreifen. Sophisticated ICR pulse event programs were developed to enable long-range ion–ion interactions between simultaneously trapped positive and negative ions. Dual polarities multisegmented ICR cells were invented and deeply characterized. The gas-phase ion chemistry of several trifluoromethyl-reagents such as trifluoromethyltrimethylsilane and tris(trifluoromethyl)phosphine were also investigated in ICR. Gas-phase ion–molecule reactions of several reactive inorganic compounds with a focus on phosphorous and sulfur as well as silicon chemistry were also studied in great detail. Many ICR cell characteristics such as z-axis ion ejection and coupling of radial and axial ion motions in a superposed homogeneous magnetic and inhomogeneous trapping electric field were extensively studied. A method to measure the ion flight time and to trap the ions in the ICR cell is described. With the external ion source, a time-of-flight ICR tandem instrument is built. External ion sources were invented and differential pumping schemes were developed for enabling ultrahigh vacuum condition for ICR detection, while guiding ions at relatively higher pressures, during their flight to the ICR cell. The transition from magnet sweep to frequency sweep and the application of Fourier-transform has greatly enhanced the ICR technology. For the tetrachloromethane molecular ion, m/z 166, a mass-resolving power m/Δm = 1.5 × 106 was measured at a pressure of 2 × 10−8 Torr. At this magnetic field, a trapping time of 13.5 h was obtained with 30% efficiency. An FT-ICR mass spectrometer has been developed with a high magnetic field superconducting magnet, operating at 4.7 T. In this review, a brief account is given focusing especially on the studies performed in Wanczek's group and ICR research laboratory at the University of Bremen. The world of Fourier-transform ion cyclotron resonance (FT-ICR) mass spectrometry has witnessed, especially in the last 30 years significant advances in many fields of science, such as electronics, magnets, new ICR cell designs, developed ICR event sequences, modern external ionization sources, and linear ion beam guides, as well as modern vacuum technology.
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